ATL‐derived factor (ADF), an IL‐2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol‐reduction in the IL‐2 receptor induction

HTLV‐I transformed T cells not only express a large number of interleukin‐2 receptors [IL‐2R/p55(Tac)], but also produce a factor named ATL‐derived factor (ADF) that augments the expression of IL‐2R/p55(Tac). Based on a partial N‐terminal amino acid sequence, complementary DNA (cDNA) clones for huma...

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Veröffentlicht in:	The EMBO journal 1989-03, Vol.8 (3), p.757-764
Hauptverfasser:	Tagaya, Y., Maeda, Y., Mitsui, A., Kondo, N., Matsui, H., Hamuro, J., Brown, N., Arai, K., Yokota, T., Wakasugi, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analysis of the immune response. Humoral and cellular immunity Animals Base Sequence Biological and medical sciences Cell Transformation, Viral Cloning, Molecular Cytokines Disulfides - metabolism DNA - genetics Fundamental and applied biological sciences. Psychology Fundamental immunology Human T-lymphotropic virus 1 Humans Immunobiology Lymphocyte Activation Mice Miscellaneous Molecular Sequence Data Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Oxidation-Reduction Receptors, Interleukin-2 - biosynthesis Regulatory factors and their cellular receptors T-Lymphocytes - immunology T-Lymphocytes - metabolism Thioredoxins - metabolism
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