Diagnostic and mechanistic implications of serum free light chains, albumin and alpha-fetoprotein in hepatocellular carcinoma

Background: Mass spectroscopy analysis suggested low serum albumin and high immunoglobulin free light chain (sFLC) levels may have diagnostic value in hepatocellular carcinoma (HCC). Our aims were to apply quantitative assays to confirm these observations, determine their diagnostic utility, and inv...

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Veröffentlicht in:	British journal of cancer 2014-04, Vol.110 (9), p.2277-2282
Hauptverfasser:	Teng, M, Pirrie, S, Ward, D G, Assi, L K, Hughes, R G, Stocken, D, Johnson, P J
Format:	Artikel
Sprache:	eng
Schlagworte:	692/53/2421 692/699/67/1504/1610 alpha-Fetoproteins - analysis Biological and medical sciences Biomarkers Biomarkers, Tumor - blood Biomedical and Life Sciences Biomedicine Biopsy Cancer Research Carcinoma, Hepatocellular - diagnosis Drug Resistance Epidemiology Gastroenterology. Liver. Pancreas. Abdomen Hepatitis B Hepatitis C Humans Immunoglobulin Light Chains - blood Immunoglobulins Light Liver cancer Liver cirrhosis Liver diseases Liver Neoplasms - diagnosis Liver. Biliary tract. Portal circulation. Exocrine pancreas Mass Spectrometry Medical research Medical sciences Molecular Diagnostics Molecular Medicine Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Oncology Patients Serology Serum Albumin - analysis Spectrum analysis Tumors Ultrasonic imaging
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