A Single Promoter Inversion Switches Photorhabdus Between Pathogenic and Mutualistic States

Microbial populations stochastically generate variants with strikingly different properties, such as virulence or avirulence and antibiotic tolerance or sensitivity. Photorhabdus luminescens bacteria have a variable life history in which they alternate between pathogens to a wide variety of insects...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2012-07, Vol.337 (6090), p.88-93
Hauptverfasser:	Somvanshi, Vishal S., Sloup, Rudolph E., Crawford, Jason M., Martin, Alexander R., Heidt, Anthony J., Kim, Kwi-suk, Clardy, Jon, Ciche, Todd A.
Format:	Artikel
Sprache:	eng
Schlagworte:	adults alleles Animals Antibiotics Bacillus thuringiensis Bacteria Bacteriology Biological and medical sciences Delta cells digestive system Drug resistance entomopathogenic nematodes field experimentation Fimbriae Proteins - genetics Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Bacterial Genes Genetics Genome, Bacterial Infections Insect colonies Insects Intestines Intestines - microbiology luminescence Microbiology Moths - microbiology Mutation Mutualism Nematoda Nematodes Nutrients Pathogenesis Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Pathogens Phenotype Phenotypes Photorhabdus Photorhabdus - cytology Photorhabdus - genetics Photorhabdus - growth & development Photorhabdus - pathogenicity Photorhabdus luminescens Promoter Regions, Genetic Rhabditoidea - microbiology Sequence Inversion social behavior Switches Symbiosis Toxins Virulence Virulence - genetics
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