BMP6 reverses TGF-β1-induced changes in HK-2 cells： implications for the treatment of renal fibrosis

Aim： The aim of the study was to investigate the potential role of BMP6 in TGF-β1-mediated changes in HK-2 cells. Methods： BMP6 was purified via heparin affinity and reverse phase liquid chromatography. The purity, specificity, and bioactivity of BMP6 were determined by SDS-PAGE, Western blot assays...

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Veröffentlicht in:	Acta pharmacologica Sinica 2009-06, Vol.30 (7), p.994-1000
Hauptverfasser:	Yan, Ji-dong, Yang, Shuang, Zhang, Jie, Zhu, Tian-hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Immunology Internal Medicine Medical Microbiology Original original-article Pharmacology/Toxicology Vaccine 临床分析 活性测定方法 活性酶 生物技术 聚合酶
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