$Human immune cells＇ behavior and survival under bioenergetically restricted conditions in an in vitro fracture hematoma model$

Human immune cells＇ behavior and survival under bioenergetically restricted conditions in an in vitro fracture hematoma model

The initial inflammatory phase of bone fracture healing represents a critical step for the outcome of the healing process. However, both the mechanisms initiating this inflammatory phase and the function of immune cells present at the fracture site are poorly understood. In order to study the early...

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Veröffentlicht in:	Cellular & molecular immunology 2013-03, Vol.10 (2), p.151-158
Hauptverfasser:	Hoff, Paula, Maschmeyer, Patrick, Gaber, Timo, Schütze, Tabea, Raue, Tobias, Schmidt-Bleek, Katharina, Dziurla, René, Schellmann, Saskia, Lohanatha, Ferenz Leonard, Röhner, Eric, Ode, Andrea, Burmester, Gerd-Rüdiger, Duda, Georg N, Perka, Carsten, Buttgereit, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angiogenesis Antibodies Apoptosis Arthroplasty, Replacement, Hip - methods Biomedical and Life Sciences Biomedicine Bone healing Cell survival Cell Survival - immunology Cells, Cultured Chemokine CCL2 - secretion Chemotactic factors Controlled conditions Cytokines Energy Metabolism - immunology Female Femur Femur - surgery Fractures Fractures, Bone - immunology Fractures, Bone - metabolism Fractures, Bone - pathology Hematoma Hematoma - immunology Hematoma - metabolism Hematoma - pathology Humans Hypoxia Immunology Inflammation Interferon-gamma - secretion Interleukin-6 - secretion Interleukin-8 - secretion Leukocytes (neutrophilic) Lymphocytes Male Medical Microbiology Microbiology Middle Aged Osteotomy research-article Total hip arthroplasty Vaccine Vascular Endothelial Growth Factor A - secretion Wound Healing - immunology 体外免疫细胞断裂模型生物能量血肿量限骨折愈合
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