Contribution of functional KIR3DL1 to ankylosing spondylitis

Increasing evidence points to a role for killer immunoglobulin-like receptors (KIRs) in the development of autoimmune diseases. In particular, a positive association of KIR3DS1 (activating receptor) and a negative association of KIR3DL1 (inhibitory receptor) alleles with ankylosing spondylitis (AS)...

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Veröffentlicht in:	Cellular & molecular immunology 2010-11, Vol.7 (6), p.471-476
Hauptverfasser:	Zvyagin, Ivan V, Mamedov, Ilgar Z, Britanova, Olga V, Staroverov, Dmitriy B, Nasonov, Evgeni L, Bochkova, Anna G, Chkalina, Anna V, Kotlobay, Alexei A, Korostin, Dmitriy O, Rebrikov, Denis V, Lukyanov, Sergey, Lebedev, Yuri B, Chudakov, Dmitriy M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Ankylosing spondylitis Antibodies Arthritis Autoimmune diseases Biomedical and Life Sciences Biomedicine Case-Control Studies European Continental Ancestry Group - genetics Gene frequency Gene Frequency - genetics Genotypes Heterozygote Histocompatibility antigen HLA Humans Immunoglobulin-like receptors Immunology Lymphocytes T Medical Microbiology Microbiology Middle Aged Natural killer cells Potassium channels (inwardly-rectifying) Receptors, KIR3DL1 - genetics Receptors, KIR3DS1 - genetics research-article Russia Spain Spondylitis, Ankylosing - genetics Vaccine
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