Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer's disease

Amyloid β (Aβ) peptides have long been viewed as a potential target for Alzheimer's disease (AD). Aggregation of Aβ peptides in the brain tissue is believed to be an exclusively pathological process. Therefore, blocking the initial stages of Aβ peptide aggregation with small molecules could hol...

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Veröffentlicht in:Acta pharmacologica Sinica 2011-05, Vol.32 (5), p.545-551
Hauptverfasser: Nie, Qin, Du, Xiao-guang, Geng, Mei-yu
Format: Artikel
Sprache:eng
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