Rearrangement and expression of the immunoglobulin μ-chain gene in human myeloid cells

Immunoglobulin （Ig）, a characteristic marker of B cells, has been reported to be expressed in epithelial cells, with a suggested role in their growth and survival. We have previously reported that IgG heavy chain is expressed in acute myeloid leukemia （AML）, but not in the monocytes or neutrophils f...

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Veröffentlicht in:	Cellular & molecular immunology 2014-01, Vol.11 (1), p.94-104
Hauptverfasser:	Huang, Jing, Sun, Xiaoping, Gong, Xiaoting, He, Zhiqiao, Chen, Lei, Qiu, Xiaoyan, Yin, C Cameron
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Adolescent Adult Aged Aged, 80 and over Antibodies Apoptosis Biomedical and Life Sciences Biomedicine Blotting, Western B细胞 Case-Control Studies Cell Proliferation Child Child, Preschool Epithelial cells Female Flow Cytometry Gene Rearrangement Healthy Volunteers Humans IgM抗体 Immunoenzyme Techniques Immunoglobulin G Immunoglobulin Heavy Chains - genetics Immunoglobulin M Immunoglobulin M - genetics Immunoglobulin mu-Chains - genetics Immunoglobulin Variable Region - genetics Immunoglobulins Immunology Immunophenotyping Immunoprecipitation Leukemia, Myeloid, Acute - genetics Leukemogenesis Leukocytes (neutrophilic) Lymphocytes B Male Medical Microbiology Microbiology Middle Aged Minimal residual disease Monocytes Monocytes - immunology Monocytes - metabolism Myeloid cells Myeloid Cells - metabolism Myeloid Cells - pathology Neoplasia Neoplasms - genetics Neutrophils Neutrophils - immunology Neutrophils - metabolism Real-Time Polymerase Chain Reaction research-article Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Somatic hypermutation Somatic Hypermutation, Immunoglobulin - genetics Tumor Cells, Cultured Tumors Vaccine Young Adult 免疫球蛋白分子标记单核细胞嗜中性粒细胞基因重排链表
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