Seminal vesicle agenesis: An uncommon cause of azoospermia

Seminal vesicle agenesis: An uncommon cause of azoospermia

Seminal vesicle malformations are a rare cause of obstructive azoospermia, often associated with other internal genitalia and upper urinary tract birth defects. We report 5 new cases of seminal vesicle agenesis in men presenting with hypospermia and azoospermia. Imaging showed seminal vesicle unilat...

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Veröffentlicht in:Canadian Urological Association journal 2014-03, Vol.8 (3-4), p.E266-E269
Hauptverfasser: Bouzouita, Abderrazak, Kerkeni, Walid, Abouda, Hassine, Khrouf, Mohamed, Elloumi, Hanene, Mnif, Najla, Messaoud, Taieb, Zhioua, Amel, Zhioua, Fethi, Chebil, Mohamed
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Case Series
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container_end_page E269
container_issue 3-4
container_start_page E266
container_title Canadian Urological Association journal
container_volume 8
creator Bouzouita, Abderrazak
Kerkeni, Walid
Abouda, Hassine
Khrouf, Mohamed
Elloumi, Hanene
Mnif, Najla
Messaoud, Taieb
Zhioua, Amel
Zhioua, Fethi
Chebil, Mohamed
description Seminal vesicle malformations are a rare cause of obstructive azoospermia, often associated with other internal genitalia and upper urinary tract birth defects. We report 5 new cases of seminal vesicle agenesis in men presenting with hypospermia and azoospermia. Imaging showed seminal vesicle unilateral agenesis in all patients. The remaining seminal vesicle was hypoplastic in 3 cases, dilated in 1 case and with abnormally thick content in another case. Vas deferens agenesis was observed unilaterally in 2 patients and bilaterally in 2 other patients. No renal malformations were detected. Genetic study showed in all cases a 46 XY karyotype without any microdeletions. A single heterozygous cystic fibrosis transmembrane regulator gene mutation was diagnosed in 1 man, but not found in his partner. Intracytoplasmic sperm injection using sperm from a testicular biopsy was performed in 3 couples, without success.
doi_str_mv 10.5489/cuaj.1663
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1920-1214
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title Seminal vesicle agenesis: An uncommon cause of azoospermia
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