Leptin-promoted cilia assembly is critical for normal energy balance

The majority of mammalian cells have nonmotile primary cilia on their surface that act as antenna-like sensory organelles. Genetic defects that result in ciliary dysfunction are associated with obesity in humans and rodents, which suggests that functional cilia are important for controlling energy b...

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Veröffentlicht in:The Journal of clinical investigation 2014-05, Vol.124 (5), p.2193-2197
Hauptverfasser: Han, Yu Mi, Kang, Gil Myoung, Byun, Kyunghee, Ko, Hyuk Wan, Kim, Joon, Shin, Mi-Seon, Kim, Hyun-Kyong, Gil, So Young, Yu, Ji Hee, Lee, Bonghee, Kim, Min-Seon
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Sprache:eng
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