Leptin-promoted cilia assembly is critical for normal energy balance
The majority of mammalian cells have nonmotile primary cilia on their surface that act as antenna-like sensory organelles. Genetic defects that result in ciliary dysfunction are associated with obesity in humans and rodents, which suggests that functional cilia are important for controlling energy b...
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Veröffentlicht in: | The Journal of clinical investigation 2014-05, Vol.124 (5), p.2193-2197 |
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Format: | Artikel |
Sprache: | eng |
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