Adverse neurodevelopmental outcomes after exposure to phenobarbital and levetiracetam for the treatment of neonatal seizures

Objective: Compare neurodevelopment after levetiracetam (LEV) and phenobarbital (PB) for neonatal seizures. Study design: Retrospective study of infants who received antiepileptic drugs (AEDs) for neonatal seizures. Effect of cumulative exposure to LEV and PB on outcomes of death, cerebral palsy (CP...

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Veröffentlicht in:	Journal of perinatology 2013-11, Vol.33 (11), p.841-846
Hauptverfasser:	Maitre, N L, Smolinsky, C, Slaughter, J C, Stark, A R
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/375/178 692/699/375/2764 692/700/565/1436 692/700/565/2194 Anticonvulsants - administration & dosage Anticonvulsants - adverse effects Antiepileptic agents Care and treatment Cerebral palsy Child Development - drug effects Child, Preschool Cognitive ability Cohort Studies Convulsions & seizures Dosage and administration Drug development Drug dosages Drug therapy Electroencephalography Etiology Etiracetam Exposure Gestational Age Hospitals Humans Infant Infant, Newborn Infant, Newborn, Diseases - drug therapy Infants Infants (Premature) Ischemia Levetiracetam Medical records Medicine Medicine & Public Health Metabolism Neonates Neurodevelopment Newborn babies original-article Paralysis Pediatric Surgery Pediatrics Pharmacy Phenobarbital Phenobarbital - administration & dosage Phenobarbital - adverse effects Piracetam - administration & dosage Piracetam - adverse effects Piracetam - analogs & derivatives Retrospective Studies Seizures Seizures (Medicine) Seizures - drug therapy
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