The global landscape of intron retentions in lung adenocarcinoma

The transcriptome complexity in an organism can be achieved by alternative splicing of precursor messenger RNAs. It has been revealed that alternations in mRNA splicing play an important role in a number of diseases including human cancers. In this study, we exploited whole transcriptome sequencing...

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Veröffentlicht in:	BMC medical genomics 2014-03, Vol.7 (1), p.15-15, Article 15
Hauptverfasser:	Zhang, Qu, Li, Hua, Jin, Hong, Tan, Huibiao, Zhang, Jun, Sheng, Sitong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - genetics Adenocarcinoma of Lung Analysis Development and progression Epidermal growth factor Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Ontology Genes, Neoplasm Genetic aspects Genome, Human - genetics Humans Introns - genetics Kinases Lung cancer Lung Neoplasms - genetics Medical research Medicine, Experimental Mortality Mutation Nonsense Mediated mRNA Decay - genetics Patients Physiological aspects Retention Risk factors RNA sequencing RNA Splicing - genetics Rodents Studies Tumors
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