Hepatocyte specific HMGB1 deletion worsens the injury in liver ischemia/reperfusion: A role for intracellular HMGB1 in cellular protection

High mobility group box-1 (HMGB1) is an abundant chromatin associated nuclear protein and released into the extracellular milieu during liver ischemia/reperfusion (I/R), signaling the activation of pro-inflammatory cascades. Since the intracellular function of HMGB1 during the sterile inflammation o...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2014-04, Vol.59 (5), p.1984-1997
Hauptverfasser:	Huang, Hai, Nace, Gary W., McDonald, Kerry-Ann, Tai, Sheng, Klune, John R., Rosborough, Brian R., Ding, Qing, Loughran, Patricia, Zhu, Xiaorong, Beer-Stolz, Donna, Chang, Eugene B., Billiar, Timothy, Tsung, Allan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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