BHBA Suppresses LPS-Induced Inflammation in BV-2 Cells by Inhibiting NF-κB Activation

β-Hydroxybutyric acid (BHBA) has neuroprotective effects, but the underlying molecular mechanisms are unclear. Microglial activation plays an important role in neurodegenerative diseases by producing several proinflammatory enzymes and proinflammatory cytokines. The current study investigates the po...

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Veröffentlicht in:	Mediators of Inflammation 2014-01, Vol.2014 (10), p.92-103
Hauptverfasser:	Lei, Lian-Cheng, Liu, Guowen, Wang, Wei, Liu, Ju-xiong, Huang, Bing-Xu, Liu, Hong-Mei, Xue, Wen-Jing, Xie, Shan-Shan, Li, Yang, Wang, Jian-Fa, Li, Su-nan, Fu, Shou-Peng, Lv, Qing-Kang
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Hydroxybutyric Acid - pharmacology Animals Cell Line I-kappa B Proteins - metabolism Inflammation - chemically induced Inflammation - metabolism Lipopolysaccharides - pharmacology Mice NF-kappa B NF-KappaB Inhibitor alpha Signal Transduction - drug effects
Online-Zugang:	Volltext
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