Childhood intussusceptions at a tertiary care hospital in northwestern Tanzania: a diagnostic and therapeutic challenge in resource-limited setting
Intussusception remains a common cause of bowel obstruction in children and results in significant morbidity and mortality if not promptly treated. There is a paucity of prospective studies regarding childhood intussusception in Tanzania and particularly the study area. This study describes the patt...
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description | Intussusception remains a common cause of bowel obstruction in children and results in significant morbidity and mortality if not promptly treated. There is a paucity of prospective studies regarding childhood intussusception in Tanzania and particularly the study area. This study describes the pattern, clinical presentations and management outcomes of childhood intussusception in our setting and highlights the challenging problems in the management of this disease.
This was a prospective descriptive study of patients aged < 10 years operated for intussusception at Bugando Medical Centre. Ethical approval to conduct the study was obtained from relevant authorities. Data was analyzed using SPSS version 17.0.
A total of 56 patients were studied. The male to female ratio was 3.3: 1. The median age was 6 months. Three-quarter of patients were < 1 year. Etiology was mainly idiopathic in 91.1% of cases. The classic triad of bloody stool, vomiting and abdominal distention/abdominal pain was found in 24 (42.5%) patients. The diagnosis of intussusception was mainly clinically in 71.4% of cases. All patients were treated surgically. Ileo-colic was the most frequent type of intussusception (67.9%). Twenty-six (46.4%) patients required bowel resection. The rate of bowel resection was significantly associated with late presentation > 24 hour (p = 0.001). Complication rate was 32.1% and surgical site infection (37.5%) was the most frequent complication. The median length of hospital stay was 7 days. Patients who had bowel resection and those who developed complications stayed longer in the hospital and this was statistically significant (p < 0.001). Mortality rate was 14.3%. Age < 1 year, delayed presentation, associated peritonitis, bowel resection and surgical site infection were the main predictors of mortality (p < 0.001). The follow up of patients was generally poor
Intussusception in our setting is characterized by late presentation, lack of specialized facilities and trained personnel for nonsurgical reduction. Therefore, surgery remains the main stay of treatment in our centre. A high index of suspicion and proper evaluation of patients is essential for an early diagnosis and timely definitive treatment, in order to decrease the morbidity and mortality associated with this disease. |
doi_str_mv | 10.1186/1824-7288-40-28 |
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This was a prospective descriptive study of patients aged < 10 years operated for intussusception at Bugando Medical Centre. Ethical approval to conduct the study was obtained from relevant authorities. Data was analyzed using SPSS version 17.0.
A total of 56 patients were studied. The male to female ratio was 3.3: 1. The median age was 6 months. Three-quarter of patients were < 1 year. Etiology was mainly idiopathic in 91.1% of cases. The classic triad of bloody stool, vomiting and abdominal distention/abdominal pain was found in 24 (42.5%) patients. The diagnosis of intussusception was mainly clinically in 71.4% of cases. All patients were treated surgically. Ileo-colic was the most frequent type of intussusception (67.9%). Twenty-six (46.4%) patients required bowel resection. The rate of bowel resection was significantly associated with late presentation > 24 hour (p = 0.001). Complication rate was 32.1% and surgical site infection (37.5%) was the most frequent complication. The median length of hospital stay was 7 days. Patients who had bowel resection and those who developed complications stayed longer in the hospital and this was statistically significant (p < 0.001). Mortality rate was 14.3%. Age < 1 year, delayed presentation, associated peritonitis, bowel resection and surgical site infection were the main predictors of mortality (p < 0.001). The follow up of patients was generally poor
Intussusception in our setting is characterized by late presentation, lack of specialized facilities and trained personnel for nonsurgical reduction. Therefore, surgery remains the main stay of treatment in our centre. A high index of suspicion and proper evaluation of patients is essential for an early diagnosis and timely definitive treatment, in order to decrease the morbidity and mortality associated with this disease.</description><identifier>ISSN: 1824-7288</identifier><identifier>ISSN: 1720-8424</identifier><identifier>EISSN: 1824-7288</identifier><identifier>DOI: 10.1186/1824-7288-40-28</identifier><identifier>PMID: 24618338</identifier><language>eng</language><publisher>England: BioMed Central</publisher><subject>Abdomen ; Age ; Child ; Child, Preschool ; Colleges & universities ; Cost-Benefit Analysis ; Data analysis ; Diagnosis, Differential ; Digestive System Surgical Procedures - methods ; Female ; Follow-Up Studies ; Hospitalization ; Hospitals ; Humans ; Infant ; Intussusception - diagnosis ; Intussusception - epidemiology ; Intussusception - surgery ; Male ; Morbidity ; Mortality ; Population ; Prevalence ; Prospective Studies ; Surgery ; Tanzania - epidemiology ; Tertiary Care Centers - economics ; Treatment Outcome</subject><ispartof>Italian journal of pediatrics, 2014-03, Vol.40 (1), p.28-28, Article 28</ispartof><rights>2014 Chalya et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.</rights><rights>Copyright © 2014 Chalya et al.; licensee BioMed Central Ltd. 2014 Chalya et al.; licensee BioMed Central Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b547t-22a368d5c22983cbee6c20987509b7e8f187e33a25433b0a46ebf8aaf7dee3263</citedby><cites>FETCH-LOGICAL-b547t-22a368d5c22983cbee6c20987509b7e8f187e33a25433b0a46ebf8aaf7dee3263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995784/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995784/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24618338$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chalya, Phillipo L</creatorcontrib><creatorcontrib>Kayange, Neema M</creatorcontrib><creatorcontrib>Chandika, Alphonce B</creatorcontrib><title>Childhood intussusceptions at a tertiary care hospital in northwestern Tanzania: a diagnostic and therapeutic challenge in resource-limited setting</title><title>Italian journal of pediatrics</title><addtitle>Ital J Pediatr</addtitle><description>Intussusception remains a common cause of bowel obstruction in children and results in significant morbidity and mortality if not promptly treated. There is a paucity of prospective studies regarding childhood intussusception in Tanzania and particularly the study area. This study describes the pattern, clinical presentations and management outcomes of childhood intussusception in our setting and highlights the challenging problems in the management of this disease.
This was a prospective descriptive study of patients aged < 10 years operated for intussusception at Bugando Medical Centre. Ethical approval to conduct the study was obtained from relevant authorities. Data was analyzed using SPSS version 17.0.
A total of 56 patients were studied. The male to female ratio was 3.3: 1. The median age was 6 months. Three-quarter of patients were < 1 year. Etiology was mainly idiopathic in 91.1% of cases. The classic triad of bloody stool, vomiting and abdominal distention/abdominal pain was found in 24 (42.5%) patients. The diagnosis of intussusception was mainly clinically in 71.4% of cases. All patients were treated surgically. Ileo-colic was the most frequent type of intussusception (67.9%). Twenty-six (46.4%) patients required bowel resection. The rate of bowel resection was significantly associated with late presentation > 24 hour (p = 0.001). Complication rate was 32.1% and surgical site infection (37.5%) was the most frequent complication. The median length of hospital stay was 7 days. Patients who had bowel resection and those who developed complications stayed longer in the hospital and this was statistically significant (p < 0.001). Mortality rate was 14.3%. Age < 1 year, delayed presentation, associated peritonitis, bowel resection and surgical site infection were the main predictors of mortality (p < 0.001). The follow up of patients was generally poor
Intussusception in our setting is characterized by late presentation, lack of specialized facilities and trained personnel for nonsurgical reduction. Therefore, surgery remains the main stay of treatment in our centre. A high index of suspicion and proper evaluation of patients is essential for an early diagnosis and timely definitive treatment, in order to decrease the morbidity and mortality associated with this disease.</description><subject>Abdomen</subject><subject>Age</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Colleges & universities</subject><subject>Cost-Benefit Analysis</subject><subject>Data analysis</subject><subject>Diagnosis, Differential</subject><subject>Digestive System Surgical Procedures - methods</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hospitalization</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infant</subject><subject>Intussusception - diagnosis</subject><subject>Intussusception - epidemiology</subject><subject>Intussusception - surgery</subject><subject>Male</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Population</subject><subject>Prevalence</subject><subject>Prospective Studies</subject><subject>Surgery</subject><subject>Tanzania - epidemiology</subject><subject>Tertiary Care Centers - economics</subject><subject>Treatment Outcome</subject><issn>1824-7288</issn><issn>1720-8424</issn><issn>1824-7288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kstu1TAQhiMEoqWwZocssWET6lsShwUSHHGTKrEpa2viTE5cJXawHRB9jb4wjk45ahGsbM98_jXzzxTFc0ZfM6bqc6a4LBuuVClpydWD4vQYeXjnflI8ifGKUsGrmj0uTrismRJCnRY3u9FO_eh9T6xLa4xrNLgk610kkAiQhCFZCL-IgYBk9HGxCaYME-dDGn9izIQjl-CuwVl4k7_0FvbOx2QNAdeTNGKABdftbUaYJnR73AQCRr8Gg-VkZ5uwJxFTsm7_tHg0wBTx2e15Vnz7-OFy97m8-Prpy-7dRdlVskkl5yBq1VeG81YJ0yHWhtNWNRVtuwbVwFSDQgCvpBAdBVljNyiAoekRBa_FWfH2oLus3Yy9QZcCTHoJds4Naw9W3884O-q9_6FF21aNklng_UGgs_4_Avczxs96G4rehqIl1VxlkVe3VQT_fc126tnmGUwTOPRr1Cy3I5mg1Ya-_Au9yga67FGmWFPLKi9Fps4PlAk-xoDDsSBG9bY1_yjhxV0jjvyfNRG_ASJKwjo</recordid><startdate>20140311</startdate><enddate>20140311</enddate><creator>Chalya, Phillipo L</creator><creator>Kayange, Neema M</creator><creator>Chandika, Alphonce B</creator><general>BioMed Central</general><general>BioMed Central Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140311</creationdate><title>Childhood intussusceptions at a tertiary care hospital in northwestern Tanzania: a diagnostic and therapeutic challenge in resource-limited setting</title><author>Chalya, Phillipo L ; Kayange, Neema M ; Chandika, Alphonce B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b547t-22a368d5c22983cbee6c20987509b7e8f187e33a25433b0a46ebf8aaf7dee3263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Abdomen</topic><topic>Age</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Colleges & universities</topic><topic>Cost-Benefit Analysis</topic><topic>Data analysis</topic><topic>Diagnosis, Differential</topic><topic>Digestive System Surgical Procedures - methods</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hospitalization</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Infant</topic><topic>Intussusception - diagnosis</topic><topic>Intussusception - epidemiology</topic><topic>Intussusception - surgery</topic><topic>Male</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>Population</topic><topic>Prevalence</topic><topic>Prospective Studies</topic><topic>Surgery</topic><topic>Tanzania - epidemiology</topic><topic>Tertiary Care Centers - economics</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chalya, Phillipo L</creatorcontrib><creatorcontrib>Kayange, Neema M</creatorcontrib><creatorcontrib>Chandika, Alphonce B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Italian journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chalya, Phillipo L</au><au>Kayange, Neema M</au><au>Chandika, Alphonce B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Childhood intussusceptions at a tertiary care hospital in northwestern Tanzania: a diagnostic and therapeutic challenge in resource-limited setting</atitle><jtitle>Italian journal of pediatrics</jtitle><addtitle>Ital J Pediatr</addtitle><date>2014-03-11</date><risdate>2014</risdate><volume>40</volume><issue>1</issue><spage>28</spage><epage>28</epage><pages>28-28</pages><artnum>28</artnum><issn>1824-7288</issn><issn>1720-8424</issn><eissn>1824-7288</eissn><abstract>Intussusception remains a common cause of bowel obstruction in children and results in significant morbidity and mortality if not promptly treated. There is a paucity of prospective studies regarding childhood intussusception in Tanzania and particularly the study area. This study describes the pattern, clinical presentations and management outcomes of childhood intussusception in our setting and highlights the challenging problems in the management of this disease.
This was a prospective descriptive study of patients aged < 10 years operated for intussusception at Bugando Medical Centre. Ethical approval to conduct the study was obtained from relevant authorities. Data was analyzed using SPSS version 17.0.
A total of 56 patients were studied. The male to female ratio was 3.3: 1. The median age was 6 months. Three-quarter of patients were < 1 year. Etiology was mainly idiopathic in 91.1% of cases. The classic triad of bloody stool, vomiting and abdominal distention/abdominal pain was found in 24 (42.5%) patients. The diagnosis of intussusception was mainly clinically in 71.4% of cases. All patients were treated surgically. Ileo-colic was the most frequent type of intussusception (67.9%). Twenty-six (46.4%) patients required bowel resection. The rate of bowel resection was significantly associated with late presentation > 24 hour (p = 0.001). Complication rate was 32.1% and surgical site infection (37.5%) was the most frequent complication. The median length of hospital stay was 7 days. Patients who had bowel resection and those who developed complications stayed longer in the hospital and this was statistically significant (p < 0.001). Mortality rate was 14.3%. Age < 1 year, delayed presentation, associated peritonitis, bowel resection and surgical site infection were the main predictors of mortality (p < 0.001). The follow up of patients was generally poor
Intussusception in our setting is characterized by late presentation, lack of specialized facilities and trained personnel for nonsurgical reduction. Therefore, surgery remains the main stay of treatment in our centre. A high index of suspicion and proper evaluation of patients is essential for an early diagnosis and timely definitive treatment, in order to decrease the morbidity and mortality associated with this disease.</abstract><cop>England</cop><pub>BioMed Central</pub><pmid>24618338</pmid><doi>10.1186/1824-7288-40-28</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Abdomen Age Child Child, Preschool Colleges & universities Cost-Benefit Analysis Data analysis Diagnosis, Differential Digestive System Surgical Procedures - methods Female Follow-Up Studies Hospitalization Hospitals Humans Infant Intussusception - diagnosis Intussusception - epidemiology Intussusception - surgery Male Morbidity Mortality Population Prevalence Prospective Studies Surgery Tanzania - epidemiology Tertiary Care Centers - economics Treatment Outcome |
title | Childhood intussusceptions at a tertiary care hospital in northwestern Tanzania: a diagnostic and therapeutic challenge in resource-limited setting |
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