Sonic hedgehog pathway contributes to gastric cancer cell growth and proliferation

The Sonic Hedgehog (Shh) signaling pathway is commonly activated in gastrointestinal cancer. However, our understanding of the Shh pathway in gastric cancer remains limited. Here we examined the effects of cyclopamine, a specific inhibitor of the Shh signaling pathway, on cell growth and proliferati...

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Veröffentlicht in:BioResearch open access 2014-04, Vol.3 (2), p.53-59
Hauptverfasser: Wan, Jianhua, Zhou, Ji, Zhao, Hailong, Wang, Mei, Wei, Zhuanqin, Gao, Hongyan, Wang, Yongzhong, Cui, Hongjuan
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Sprache:eng
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