Protection of mice against Shiga toxin 2 (Stx2)-associated damage by maternal immunization with a Brucella lumazine synthase-Stx2 B subunit chimera

Hemolytic-uremic syndrome (HUS) is defined as the triad of anemia, thrombocytopenia, and acute kidney injury. Enterohemorrhagic Shiga toxin (Stx)-producing Escherichia coli (EHEC), which causes a prodromal hemorrhagic enteritis, remains the most common etiology of the typical or epidemic form of HUS...

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Veröffentlicht in:	Infection and immunity 2014-04, Vol.82 (4), p.1491-1499
Hauptverfasser:	Mejias, María Pilar, Cabrera, Gabriel, Fernández-Brando, Romina Jimena, Baschkier, Ariela, Ghersi, Giselle, Abrey-Recalde, Maria Jimena, Miliwebsky, Elizabeth, Meiss, Roberto, Goldbaum, Fernando, Zylberman, Vanesa, Rivas, Marta, Palermo, Marina Sandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Bacterial - analysis Brucella Brucella - immunology Disease Models, Animal Enterohemorrhagic Escherichia coli Escherichia coli Escherichia coli Infections - immunology Female Hemolytic-Uremic Syndrome - microbiology Hemolytic-Uremic Syndrome - prevention & control Immunity, Maternally-Acquired - immunology Immunization - methods Mice Mice, Inbred BALB C Microbial Immunity and Vaccines Multienzyme Complexes - immunology Recombinant Fusion Proteins - immunology Shiga Toxin 2 - immunology Shigella Vaccines - immunology
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