Trichomonas vaginalis Metronidazole Resistance Is Associated with Single Nucleotide Polymorphisms in the Nitroreductase Genes ntr4Tv and ntr6Tv

Metronidazole resistance in the sexually transmitted parasite Trichomonas vaginalis is a problematic public health issue. We have identified single nucleotide polymorphisms (SNPs) in two nitroreductase genes (ntr4Tv and ntr6Tv) associated with resistance. These SNPs were associated with one of two d...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Antimicrobial agents and chemotherapy 2014-05, Vol.58 (5), p.2938-2943
Hauptverfasser:	PAULISH-MILLER, Teresa E, AUGOSTINI, Peter, SCHUYLER, Jessica A, SMITH, William L, MORDECHAI, Eli, ADELSON, Martin E, GYGAX, Scott E, SECOR, William E, HILBERT, David W
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antiprotozoal Agents - pharmacology Biological and medical sciences Codon, Terminator - genetics Drug Resistance - genetics Mechanisms of Resistance Medical sciences Metronidazole Metronidazole - pharmacology Nitroreductases Nitroreductases - genetics Parasitic Sensitivity Tests Pharmacology. Drug treatments Polymorphism, Single Nucleotide Protozoan Proteins Protozoan Proteins - genetics Trichomonas vaginalis Trichomonas vaginalis - drug effects Trichomonas vaginalis - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!