The vOTU domain of highly-pathogenic porcine reproductive and respiratory syndrome virus displays a differential substrate preference

Abstract Arterivirus genus member Porcine reproductive and respiratory syndrome virus (PRRSV) causes an economically devastating disease, recently exacerbated by the emergence of highly pathogenic strains (HP-PRRSV). Within the nonstructural protein 2 of PRRSV is a deubiquitinating enzyme domain bel...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2014-04, Vol.454, p.247-253
Hauptverfasser:	Deaton, Michelle K, Spear, Allyn, Faaberg, Kay S, Pegan, Scott D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Infectious Disease ISG15 nsp2 PLP2 Porcine respiratory and reproductive syndrome virus Porcine respiratory and reproductive syndrome virus - enzymology Porcine respiratory and reproductive syndrome virus - isolation & purification PRRSV Substrate Specificity Swine Ubiquitin Ubiquitin-Specific Proteases - metabolism Viral Nonstructural Proteins - metabolism Virulence Factors - metabolism vOTU
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