High‐titre circulating tissue transglutaminase‐2 antibodies predict small bowel villous atrophy, but decision cut‐off limits must be locally validated

Summary Numerous studies suggest that high levels of circulating immunoglobulin (Ig)A tissue transglutaminase (TTG2) antibodies predict coeliac disease with high specificity. Accordingly, it has been suggested that duodenal biopsy may not be required routinely for diagnostic confirmation where quant...

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