CpG-oligodeoxynucleotides suppress the proliferation of A549 lung adenocarcinoma cells via toll-like receptor 9 signaling and upregulation of Runt-related transcription factor 3 expression

The aim of the present study was to investigate the effect of CpG-oligodeoxynucelotides (CpG-ODN) on the proliferation of the A549 human lung adenocarcinoma cell line and the expression of Runt-related transcription factor 3 (Runx3) and investigate the association between the toll-like receptor 9 (T...

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Veröffentlicht in:	Biomedical reports 2014-05, Vol.2 (3), p.374-377
Hauptverfasser:	BARNIE, PRINCE AMOAH, ZHANG, PAN, LU, PING, CHEN, XIAOBO, SU, ZHAOLIANG, WANG, SHENGJUN, XU, HUAXI
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 cancer cells Adenocarcinoma Apoptosis Cell growth Cell proliferation Chemical synthesis CpG islands CpG-oligodeoxynucleotides Deoxyribonucleic acid Development and progression DNA Gastric cancer Gene expression Genetic aspects Health aspects Immune system Investigations Lung cancer Metastasis Oligodeoxynucleotides Oligonucleotides Polymerase chain reaction proliferation Proteins Reverse transcription Runt-related transcription factor 3 Runx3 protein Signal transduction siRNA TLR9 protein toll-like receptor 9 Toll-like receptors Transcription factors Tumorigenesis
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