Expression of monocyte chemotactic protein-1/CCL2 in gastric cancer and its relationship with tumor hypoxia

AIM:To investigate the expression and prognostic value of CCL2 in gastric cancer,as well as its relationshipwith tumor hypoxia.METHODS:Tumor tissues from 68 gastric cancer patients(GC)were analyzed,and the expression of CCL2and hypoxia-inducible factor 1 alpha(HIF-1α)in tumortissues was detected by...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2014-04, Vol.20 (15), p.4421-4427
Hauptverfasser:	Tao, Lei-Lei, Shi, Shu-Jing, Chen, Long-Bang, Huang, Gui-Chun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Carcinoma - metabolism Chemokine CCL2 - metabolism Chemokines chemotactic Female Gas Gene Expression Regulation, Neoplastic Humans Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Immunohistochemistry Kaplan-Meier Estimate Male Middle Aged Monocyte Prognosis Proportional Hazards Models protein-1/CCL2 Research Report Stomach Neoplasms - metabolism Treatment Outcome
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