Sex-related differences in access to care among patients with premature acute coronary syndrome

Access to care may be implicated in disparities between men and women in death after acute coronary syndrome, especially among younger adults. We aimed to assess sex-related differences in access to care among patients with premature acute coronary syndrome and to identify clinical and gender-relate...

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Veröffentlicht in:Canadian Medical Association journal (CMAJ) 2014-04, Vol.186 (7), p.497-504
Hauptverfasser: Pelletier, Roxanne, Humphries, Karin H, Shimony, Avi, Bacon, Simon L, Lavoie, Kim L, Rabi, Doreen, Karp, Igor, Tsadok, Meytal Avgil, Pilote, Louise
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container_end_page 504
container_issue 7
container_start_page 497
container_title Canadian Medical Association journal (CMAJ)
container_volume 186
creator Pelletier, Roxanne
Humphries, Karin H
Shimony, Avi
Bacon, Simon L
Lavoie, Kim L
Rabi, Doreen
Karp, Igor
Tsadok, Meytal Avgil
Pilote, Louise
description Access to care may be implicated in disparities between men and women in death after acute coronary syndrome, especially among younger adults. We aimed to assess sex-related differences in access to care among patients with premature acute coronary syndrome and to identify clinical and gender-related determinants of access to care. We studied 1123 patients (18-55 yr) admitted to hospital for acute coronary syndrome and enrolled in the GENESIS-PRAXY cohort study. Outcome measures were door-to-electrocardiography, door-to-needle and door-to-balloon times, as well as proportions of patients undergoing cardiac catheterization, reperfusion or nonprimary percutaneous coronary intervention. We performed univariable and multivariable logistic regression analyses to identify clinical and gender-related determinants of timely procedures and use of invasive procedures. Women were less likely than men to receive care within benchmark times for electrocardiography (≤ 10 min: 29% v. 38%, p = 0.02) or fibrinolysis (≤ 30 min: 32% v. 57%, p = 0.01). Women with ST-segment elevation myocardial infarction (MI) were less likely than men to undergo reperfusion therapy (primary percutaneous coronary intervention or fibrinolysis) (83% v. 91%, p = 0.01), and women with non-ST-segment elevation MI or unstable angina were less likely to undergo nonprimary percutaneous coronary intervention (48% v. 66%, p < 0.001). Clinical determinants of poorer access to care included anxiety, increased number of risk factors and absence of chest pain. Gender-related determinants included feminine traits of personality and responsibility for housework. Among younger adults with acute coronary syndrome, women and men had different access to care. Moreover, fewer than half of men and women with ST-segment elevation MI received timely primary coronary intervention. Our results also highlight that men and women with no chest pain and those with anxiety, several traditional risk factors and feminine personality traits were at particularly increased risk of poorer access to care.
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Women with ST-segment elevation myocardial infarction (MI) were less likely than men to undergo reperfusion therapy (primary percutaneous coronary intervention or fibrinolysis) (83% v. 91%, p = 0.01), and women with non-ST-segment elevation MI or unstable angina were less likely to undergo nonprimary percutaneous coronary intervention (48% v. 66%, p &lt; 0.001). Clinical determinants of poorer access to care included anxiety, increased number of risk factors and absence of chest pain. Gender-related determinants included feminine traits of personality and responsibility for housework. Among younger adults with acute coronary syndrome, women and men had different access to care. Moreover, fewer than half of men and women with ST-segment elevation MI received timely primary coronary intervention. 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Women with ST-segment elevation myocardial infarction (MI) were less likely than men to undergo reperfusion therapy (primary percutaneous coronary intervention or fibrinolysis) (83% v. 91%, p = 0.01), and women with non-ST-segment elevation MI or unstable angina were less likely to undergo nonprimary percutaneous coronary intervention (48% v. 66%, p &lt; 0.001). Clinical determinants of poorer access to care included anxiety, increased number of risk factors and absence of chest pain. Gender-related determinants included feminine traits of personality and responsibility for housework. Among younger adults with acute coronary syndrome, women and men had different access to care. Moreover, fewer than half of men and women with ST-segment elevation MI received timely primary coronary intervention. Our results also highlight that men and women with no chest pain and those with anxiety, several traditional risk factors and feminine personality traits were at particularly increased risk of poorer access to care.</abstract><cop>Canada</cop><pub>Joule Inc</pub><pmid>24638026</pmid><doi>10.1503/cmaj.131450</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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subjects Acute Coronary Syndrome - epidemiology
Acute Coronary Syndrome - therapy
Adolescent
Adult
Canada - epidemiology
Cardiovascular disease
Care and treatment
Coronary heart disease
Diagnosis
Discrimination in medical care
Electrocardiography
Female
Follow-Up Studies
Gender differences
Health care access
Health Services Accessibility - statistics & numerical data
Humans
Incidence
Male
Medical research
Medicine, Experimental
Middle Aged
Myocardial Revascularization - methods
Prevalence
Prognosis
Prospective Studies
Risk Factors
Sex Factors
Studies
Surveys and Questionnaires
Survival Rate - trends
Switzerland - epidemiology
Thrombolytic Therapy - methods
United States - epidemiology
Young Adult
title Sex-related differences in access to care among patients with premature acute coronary syndrome
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