Improved search heuristics find 20,000 new alignments between human and mouse genomes

Sequence similarity search is a fundamental way of analyzing nucleotide sequences. Despite decades of research, this is not a solved problem because there exist many similarities that are not found by current methods. Search methods are typically based on a seed-and-extend approach, which has many v...

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Veröffentlicht in:	Nucleic acids research 2014-04, Vol.42 (7), p.e59-e59
Hauptverfasser:	Frith, Martin C, Noé, Laurent
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioinformatics Computer Science Dogs Genome Genome, Human Genomics - methods Humans Life Sciences Methods Online Mice Quantitative Methods Sequence Alignment - methods Sequence Analysis, DNA - methods
Online-Zugang:	Volltext
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