Pre–B cell colony–enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis

Pre–B cell colony-enhancing factor (PBEF) is a highly conserved 52-kDa protein, originally identified as a growth factor for early stage B cells. We show here that PBEF is also upregulated in neutrophils by IL-1β and functions as a novel inhibitor of apoptosis in response to a variety of inflammator...

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Veröffentlicht in:The Journal of clinical investigation 2004-05, Vol.113 (9), p.1318-1327
Hauptverfasser: Jia, Song Hui, Li, Yue, Parodo, Jean, Kapus, Andras, Fan, Lingzhi, Rotstein, Ori D., Marshall, John C.
Format: Artikel
Sprache:eng
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