High Field Dynamic Nuclear Polarization NMR with Surfactant Sheltered Biradicals
We illustrate the ability to place a water-insoluble biradical, bTbk, into a glycerol/water matrix with the assistance of a surfactant, sodium octyl sulfate (SOS). This surfactant approach enables a previously water insoluble biradical, bTbk, with favorable electron–electron dipolar coupling to be u...
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| Veröffentlicht in: | The journal of physical chemistry. B 2014-02, Vol.118 (7), p.1825-1830 |
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| container_issue | 7 |
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| container_title | The journal of physical chemistry. B |
| container_volume | 118 |
| creator | Kiesewetter, Matthew K Michaelis, Vladimir K Walish, Joseph J Griffin, Robert G Swager, Timothy M |
| description | We illustrate the ability to place a water-insoluble biradical, bTbk, into a glycerol/water matrix with the assistance of a surfactant, sodium octyl sulfate (SOS). This surfactant approach enables a previously water insoluble biradical, bTbk, with favorable electron–electron dipolar coupling to be used for dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) experiments in frozen, glassy, aqueous media. Nuclear Overhauser enhancement (NOE) and paramagnetic relaxation enhancement (PRE) experiments are conducted to determine the distribution of urea and several biradicals within the SOS macromolecular assembly. We also demonstrate that SOS assemblies are an effective approach by which mixed biradicals are created through an assembly process. |
| doi_str_mv | 10.1021/jp410387e |
| format | Article |
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This surfactant approach enables a previously water insoluble biradical, bTbk, with favorable electron–electron dipolar coupling to be used for dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) experiments in frozen, glassy, aqueous media. Nuclear Overhauser enhancement (NOE) and paramagnetic relaxation enhancement (PRE) experiments are conducted to determine the distribution of urea and several biradicals within the SOS macromolecular assembly. 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B</title><addtitle>J. Phys. Chem. B</addtitle><description>We illustrate the ability to place a water-insoluble biradical, bTbk, into a glycerol/water matrix with the assistance of a surfactant, sodium octyl sulfate (SOS). This surfactant approach enables a previously water insoluble biradical, bTbk, with favorable electron–electron dipolar coupling to be used for dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) experiments in frozen, glassy, aqueous media. Nuclear Overhauser enhancement (NOE) and paramagnetic relaxation enhancement (PRE) experiments are conducted to determine the distribution of urea and several biradicals within the SOS macromolecular assembly. 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| ispartof | The journal of physical chemistry. B, 2014-02, Vol.118 (7), p.1825-1830 |
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| source | ACS Publications; MEDLINE |
| subjects | Alkanesulfonic Acids - chemistry Assembly Cyclic N-Oxides - chemistry Dynamics Electrons Frozen glycerol Glycerol - chemistry Magnetic Resonance Spectroscopy - methods Molecular Structure Nuclear magnetic resonance nuclear magnetic resonance spectroscopy physical chemistry Polarization Propanols - chemistry Sodium Solubility Spiro Compounds - chemistry sulfates Surface-Active Agents - chemistry Surfactants Time Factors urea Urea - chemistry Ureas Water - chemistry |
| title | High Field Dynamic Nuclear Polarization NMR with Surfactant Sheltered Biradicals |
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