Mitotic destruction of the cell cycle regulated NIMA protein kinase of Aspergillus nidulans is required for mitotic exit

NIMA is a cell cycle regulated protein kinase required, in addition to p34cdc2/cyclin B, for initiation of mitosis in Aspergillus nidulans. Like cyclin B, NIMA accumulates when cells are arrested in G2 and is degraded as cells traverse mitosis. However, it is stable in cells arrested in mitosis. NIM...

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Veröffentlicht in:	The EMBO journal 1995-03, Vol.14 (5), p.995-1003
Hauptverfasser:	Pu, R.T, Osmani, S.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspergillus nidulans Aspergillus nidulans - cytology Aspergillus nidulans - enzymology Aspergillus nidulellus Base Sequence CDC2 Protein Kinase - physiology Cell Cycle Cell Cycle Proteins Cyclins - metabolism degradation Enzyme Induction Enzyme Stability Escherichia coli - genetics Genes, Fungal - genetics Genetic Complementation Test Mitosis Molecular Sequence Data NIMA-Related Kinase 1 NIMA-Related Kinases Protein Serine-Threonine Kinases - genetics Protein Serine-Threonine Kinases - metabolism Recombinant Proteins - biosynthesis regulation Sequence Deletion - physiology
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