Tight association between macrophages and adipocytes in obesity: Implications for adipocyte preparation

Objective To determine the cellular architecture of the inflammatory infiltrate in adipose tissue from obese mice, and identify the source of inflammatory cytokines in adipose tissue at a single cell level. Methods Adipose tissue from diet‐induced obese mice was digested by collagenase treatment and...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2014-05, Vol.22 (5), p.1246-1255
Hauptverfasser:	Ebke, Lindsey A., Nestor‐Kalinoski, Andrea L., Slotterbeck, Brandon D., Al‐Dieri, Ali G., Ghosh‐Lester, Sumona, Russo, Lucia, Najjar, Sonia M., Grafenstein, Hermann, McInerney, Marcia F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipocytes - cytology Adipocytes - ultrastructure Adipose Tissue, White - cytology Animals Cell Separation Cytokines Diet Histology Inflammation Insulin Interleukin-10 - metabolism Macrophages - cytology Macrophages - ultrastructure Male Metabolism Mice Mice, Inbred C57BL Mice, Knockout Mice, Obese Microscopy, Confocal Obesity Rodents Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - metabolism
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