Assessment of Thiopurine-based drugs according to Thiopurine S-methyltransferase genotype in patients with Acute Lymphoblastic Leukemia

For the past half century, thiopurines have earned themselves a reputation as effective anti-cancer and immunosuppressive drugs. Thiopurine S-methyltransferase (TPMT) is involved in the metabolism of all thiopurines and is one of the main enzymes that inactivates mercaptopurine. 6-MP is now used as...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Iranian journal of pediatric hematology and oncology 2014, Vol.4 (1), p.32-38
Hauptverfasser:	Azimi, F, Jafariyan, M, Khatami, S, Mortazavi, Y, Azad, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Review
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!