Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis

Since the concept of reprogramming mature somatic cells to generate induced pluripotent stem cells (iPSCs) was demonstrated in 2006, iPSCs have become a potential substitute for embryonic stem cells (ESCs) given their pluripotency and "stemness" characteristics, which resemble those of ESC...

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Veröffentlicht in:	Arthritis research & therapy 2014-02, Vol.16 (1), p.R41-R41, Article R41
Hauptverfasser:	Lee, Jaecheol, Kim, Youngkyun, Yi, Hyoju, Diecke, Sebastian, Kim, Juryun, Jung, Hyerin, Rim, Yeri Alice, Jung, Seung Min, Kim, Myungshin, Kim, Yong Goo, Park, Sung-Hwan, Kim, Ho-Youn, Ju, Ji Hyeon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis, Rheumatoid Cell Differentiation - physiology Cellular Reprogramming Chromosomes Fibroblasts - cytology Humans Induced Pluripotent Stem Cells - cytology Mice Mice, SCID Osteoarthritis Real-Time Polymerase Chain Reaction Synovial Membrane - cytology Transduction, Genetic
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