Association of Single Nucleotide Polymorphisms in Estrogen Receptor Alpha Gene with Susceptibility to Knee Osteoarthritis : A Case-Control Study in a Chinese Han Population

Osteoarthritis (OA) is the most prevalent form of arthritis and its multifactorial nature has been increasingly recognized. Genetic factors play an important role in OA etiology and estrogen receptor alpha (ESR1) gene polymorphisms may be involved. This study tried to explore whether the ESR1 gene s...

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Veröffentlicht in:	BioMed research international 2014-01, Vol.2014 (2014), p.1-12
Hauptverfasser:	Jiang, Qing, Chen, Dongyang, Xu, Zhihong, Teng, Huajian, Shi, Dongquan, Dai, Jin, Dai, Xiaoyu, Wang, Chao
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alleles Arthritis China Development and progression Diabetes Estrogen Estrogen Receptor alpha - genetics Female Gene Frequency Genes Genetic aspects Genetic Association Studies Genetic Predisposition to Disease Humans Hyperglycemia Hypertension Joint surgery Knee Male Middle Aged Osteoarthritis Osteoarthritis, Knee - etiology Osteoarthritis, Knee - genetics Osteoarthritis, Knee - pathology Polymorphism, Single Nucleotide Population Receptors Single nucleotide polymorphisms Studies
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