Calcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: a potential new therapeutic approach

Approximately 30% of breast tumors do not express the estrogen receptor (ER) α, which is necessary for endocrine therapy approaches. Studies are ongoing in order to restore ERα expression in ERα-negative breast cancer. The aim of the present study was to determine if calcitriol induces ERα expressio...

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Veröffentlicht in:	BMC cancer 2014-03, Vol.14 (1), p.230-230, Article 230
Hauptverfasser:	Santos-Martínez, Nancy, Díaz, Lorenza, Ordaz-Rosado, David, García-Quiroz, Janice, Barrera, David, Avila, Euclides, Halhali, Ali, Medina-Franco, Heriberto, Ibarra-Sánchez, María J, Esparza-López, José, Camacho, Javier, Larrea, Fernando, García-Becerra, Rocío
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - pathology Calcitriol - analogs & derivatives Calcitriol - pharmacology Cell Line, Tumor Cyclin D1 - metabolism Estradiol - analogs & derivatives Estradiol - pharmacology Estrogen Receptor alpha - genetics Estrogen Receptor alpha - metabolism Estrogen Receptor Modulators - pharmacology Estrogens Female Gene Expression Regulation, Neoplastic - drug effects Humans Kinases Receptors, Calcitriol - metabolism Rodents Vitamin D
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