Sofosbuvir, a NS5B polymerase inhibitor in the treatment of hepatitis C: a review of its clinical potential

Treatment of chronic hepatitis C (HCV) is currently undergoing a significant change. Traditional interferon-based therapy has been limited by both efficacy and tolerability, and many direct acting antiviral (DAA) drugs are emerging. Sofosbuvir (GS-7977) is a HCV NS5B nucleotide polymerase inhibitor...

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Veröffentlicht in:Therapeutic Advances in Gastroenterology 2014-05, Vol.7 (3), p.131-140
1. Verfasser: Stedman, Catherine
Format: Artikel
Sprache:eng
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