The autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spines

Copy number variation (CNV) at the 15q11.2 region has been identified as a significant risk locus for neurological and neuropsychiatric conditions such as schizophrenia (SCZ) and autism spectrum disorder (ASD). However, the individual roles for genes at this locus in nervous system development, func...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Translational psychiatry 2014-03, Vol.4 (3), p.e374-e374
Hauptverfasser:	Pathania, M, Davenport, E C, Muir, J, Sheehan, D F, López-Doménech, G, Kittler, J T
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/726/649/2157 631/378/1697/2604 692/699/476/1373 692/699/476/1799 Adaptor Proteins, Signal Transducing Animals Behavioral Sciences Biological Psychology CA1 Region, Hippocampal - metabolism CA1 Region, Hippocampal - pathology Dendrites - metabolism Dendrites - pathology Embryo, Mammalian Haploinsufficiency - genetics Male Medicine Medicine & Public Health Mice Nerve Tissue Proteins - genetics Neurosciences Original original-article Pharmacotherapy Psychiatry Rats
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!