A comparison of two methods for estimating DCE-MRI parameters via individual and cohort based AIFs in prostate cancer: A step towards practical implementation

Abstract Multi-parametric Magnetic Resonance Imaging, and specifically Dynamic Contrast Enhanced (DCE) MRI, play increasingly important roles in detection and staging of prostate cancer (PCa). One of the actively investigated approaches to DCE MRI analysis involves pharmacokinetic (PK) modeling to e...

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Veröffentlicht in:	Magnetic resonance imaging 2014-05, Vol.32 (4), p.321-329
Hauptverfasser:	Fedorov, Andriy, Fluckiger, Jacob, Ayers, Gregory D, Li, Xia, Gupta, Sandeep N, Tempany, Clare, Mulkern, Robert, Yankeelov, Thomas E, Fennessy, Fiona M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Algorithms Arterial Input Function Cohort Studies Computer Simulation Contrast Media - pharmacokinetics DCE-MRI Gadolinium DTPA - pharmacokinetics Humans Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Male Middle Aged Models, Biological Neovascularization, Pathologic - diagnosis Neovascularization, Pathologic - metabolism Pharmacokinetic modeling Pilot Projects Prostate cancer Prostatic Neoplasms - diagnosis Prostatic Neoplasms - metabolism Quantitative imaging Radiology Reproducibility of Results Sensitivity and Specificity
Online-Zugang:	Volltext
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