PATRIC, the bacterial bioinformatics database and analysis resource
The Pathosystems Resource Integration Center (PATRIC) is the all-bacterial Bioinformatics Resource Center (BRC) (http://www.patricbrc.org). A joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded BRCs, PATRIC provides researchers with an online resource tha...
Gespeichert in:
| Veröffentlicht in: | Nucleic acids research 2014-01, Vol.42 (Database issue), p.D581-D591 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | D591 |
|---|---|
| container_issue | Database issue |
| container_start_page | D581 |
| container_title | Nucleic acids research |
| container_volume | 42 |
| creator | Wattam, Alice R Abraham, David Dalay, Oral Disz, Terry L Driscoll, Timothy Gabbard, Joseph L Gillespie, Joseph J Gough, Roger Hix, Deborah Kenyon, Ronald Machi, Dustin Mao, Chunhong Nordberg, Eric K Olson, Robert Overbeek, Ross Pusch, Gordon D Shukla, Maulik Schulman, Julie Stevens, Rick L Sullivan, Daniel E Vonstein, Veronika Warren, Andrew Will, Rebecca Wilson, Meredith J C Yoo, Hyun Seung Zhang, Chengdong Zhang, Yan Sobral, Bruno W |
| description | The Pathosystems Resource Integration Center (PATRIC) is the all-bacterial Bioinformatics Resource Center (BRC) (http://www.patricbrc.org). A joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded BRCs, PATRIC provides researchers with an online resource that stores and integrates a variety of data types [e.g. genomics, transcriptomics, protein-protein interactions (PPIs), three-dimensional protein structures and sequence typing data] and associated metadata. Datatypes are summarized for individual genomes and across taxonomic levels. All genomes in PATRIC, currently more than 10,000, are consistently annotated using RAST, the Rapid Annotations using Subsystems Technology. Summaries of different data types are also provided for individual genes, where comparisons of different annotations are available, and also include available transcriptomic data. PATRIC provides a variety of ways for researchers to find data of interest and a private workspace where they can store both genomic and gene associations, and their own private data. Both private and public data can be analyzed together using a suite of tools to perform comparative genomic or transcriptomic analysis. PATRIC also includes integrated information related to disease and PPIs. All the data and integrated analysis and visualization tools are freely available. This manuscript describes updates to the PATRIC since its initial report in the 2007 NAR Database Issue. |
| doi_str_mv | 10.1093/nar/gkt1099 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3965095</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1490752900</sourcerecordid><originalsourceid>FETCH-LOGICAL-c489t-b3daea73648493a0ac14b8d067ed6f3ed2ebc2f4849992627ee6504e97ee58f93</originalsourceid><addsrcrecordid>eNpVkM1Lw0AQxRdRbK2evEuOgsbuVz72IpTgR6GgSD0vk82kXU2TupsI_e9NaS16GObBe7wZfoRcMnrHqBLjGtx48dn2Wh2RIRMxD6WK-TEZUkGjkFGZDsiZ9x-UMskieUoGXHIeCS6GJHudzN-m2W3QLjHIwbToLFRBbhtbl41bQWuNDwpoIQePAdRFP1BtvPWBQ990zuA5OSmh8nix3yPy_vgwz57D2cvTNJvMQiNT1Ya5KAAhEbFMpRJAwTCZpwWNEyziUmDBMTe83LpK8ZgniHFEJapeRGmpxIjc73rXXb7CwmDdOqj02tkVuI1uwOr_Tm2XetF8a6H6IhX1Bdf7Atd8dehbvbLeYFVBjU3nNZOKJhFXlPbRm13UuMZ7h-XhDKN6i1332PUee5---vvZIfvLWfwA07N_9Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1490752900</pqid></control><display><type>article</type><title>PATRIC, the bacterial bioinformatics database and analysis resource</title><source>Oxford Journals Open Access Collection</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Wattam, Alice R ; Abraham, David ; Dalay, Oral ; Disz, Terry L ; Driscoll, Timothy ; Gabbard, Joseph L ; Gillespie, Joseph J ; Gough, Roger ; Hix, Deborah ; Kenyon, Ronald ; Machi, Dustin ; Mao, Chunhong ; Nordberg, Eric K ; Olson, Robert ; Overbeek, Ross ; Pusch, Gordon D ; Shukla, Maulik ; Schulman, Julie ; Stevens, Rick L ; Sullivan, Daniel E ; Vonstein, Veronika ; Warren, Andrew ; Will, Rebecca ; Wilson, Meredith J C ; Yoo, Hyun Seung ; Zhang, Chengdong ; Zhang, Yan ; Sobral, Bruno W</creator><creatorcontrib>Wattam, Alice R ; Abraham, David ; Dalay, Oral ; Disz, Terry L ; Driscoll, Timothy ; Gabbard, Joseph L ; Gillespie, Joseph J ; Gough, Roger ; Hix, Deborah ; Kenyon, Ronald ; Machi, Dustin ; Mao, Chunhong ; Nordberg, Eric K ; Olson, Robert ; Overbeek, Ross ; Pusch, Gordon D ; Shukla, Maulik ; Schulman, Julie ; Stevens, Rick L ; Sullivan, Daniel E ; Vonstein, Veronika ; Warren, Andrew ; Will, Rebecca ; Wilson, Meredith J C ; Yoo, Hyun Seung ; Zhang, Chengdong ; Zhang, Yan ; Sobral, Bruno W</creatorcontrib><description>The Pathosystems Resource Integration Center (PATRIC) is the all-bacterial Bioinformatics Resource Center (BRC) (http://www.patricbrc.org). A joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded BRCs, PATRIC provides researchers with an online resource that stores and integrates a variety of data types [e.g. genomics, transcriptomics, protein-protein interactions (PPIs), three-dimensional protein structures and sequence typing data] and associated metadata. Datatypes are summarized for individual genomes and across taxonomic levels. All genomes in PATRIC, currently more than 10,000, are consistently annotated using RAST, the Rapid Annotations using Subsystems Technology. Summaries of different data types are also provided for individual genes, where comparisons of different annotations are available, and also include available transcriptomic data. PATRIC provides a variety of ways for researchers to find data of interest and a private workspace where they can store both genomic and gene associations, and their own private data. Both private and public data can be analyzed together using a suite of tools to perform comparative genomic or transcriptomic analysis. PATRIC also includes integrated information related to disease and PPIs. All the data and integrated analysis and visualization tools are freely available. This manuscript describes updates to the PATRIC since its initial report in the 2007 NAR Database Issue.</description><identifier>ISSN: 0305-1048</identifier><identifier>EISSN: 1362-4962</identifier><identifier>DOI: 10.1093/nar/gkt1099</identifier><identifier>PMID: 24225323</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Bacteria - classification ; Bacteria - genetics ; Bacterial Infections - microbiology ; Bacterial Proteins - chemistry ; Bacterial Proteins - metabolism ; Bacterial Typing Techniques ; Databases, Genetic ; Gene Expression Profiling ; Genome, Bacterial ; Genomics ; Humans ; Internet ; IV. Viruses, bacteria, protozoa and fungi ; Protein Conformation ; Protein Interaction Mapping</subject><ispartof>Nucleic acids research, 2014-01, Vol.42 (Database issue), p.D581-D591</ispartof><rights>The Author(s) 2013. Published by Oxford University Press. 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c489t-b3daea73648493a0ac14b8d067ed6f3ed2ebc2f4849992627ee6504e97ee58f93</citedby><cites>FETCH-LOGICAL-c489t-b3daea73648493a0ac14b8d067ed6f3ed2ebc2f4849992627ee6504e97ee58f93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965095/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965095/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24225323$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wattam, Alice R</creatorcontrib><creatorcontrib>Abraham, David</creatorcontrib><creatorcontrib>Dalay, Oral</creatorcontrib><creatorcontrib>Disz, Terry L</creatorcontrib><creatorcontrib>Driscoll, Timothy</creatorcontrib><creatorcontrib>Gabbard, Joseph L</creatorcontrib><creatorcontrib>Gillespie, Joseph J</creatorcontrib><creatorcontrib>Gough, Roger</creatorcontrib><creatorcontrib>Hix, Deborah</creatorcontrib><creatorcontrib>Kenyon, Ronald</creatorcontrib><creatorcontrib>Machi, Dustin</creatorcontrib><creatorcontrib>Mao, Chunhong</creatorcontrib><creatorcontrib>Nordberg, Eric K</creatorcontrib><creatorcontrib>Olson, Robert</creatorcontrib><creatorcontrib>Overbeek, Ross</creatorcontrib><creatorcontrib>Pusch, Gordon D</creatorcontrib><creatorcontrib>Shukla, Maulik</creatorcontrib><creatorcontrib>Schulman, Julie</creatorcontrib><creatorcontrib>Stevens, Rick L</creatorcontrib><creatorcontrib>Sullivan, Daniel E</creatorcontrib><creatorcontrib>Vonstein, Veronika</creatorcontrib><creatorcontrib>Warren, Andrew</creatorcontrib><creatorcontrib>Will, Rebecca</creatorcontrib><creatorcontrib>Wilson, Meredith J C</creatorcontrib><creatorcontrib>Yoo, Hyun Seung</creatorcontrib><creatorcontrib>Zhang, Chengdong</creatorcontrib><creatorcontrib>Zhang, Yan</creatorcontrib><creatorcontrib>Sobral, Bruno W</creatorcontrib><title>PATRIC, the bacterial bioinformatics database and analysis resource</title><title>Nucleic acids research</title><addtitle>Nucleic Acids Res</addtitle><description>The Pathosystems Resource Integration Center (PATRIC) is the all-bacterial Bioinformatics Resource Center (BRC) (http://www.patricbrc.org). A joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded BRCs, PATRIC provides researchers with an online resource that stores and integrates a variety of data types [e.g. genomics, transcriptomics, protein-protein interactions (PPIs), three-dimensional protein structures and sequence typing data] and associated metadata. Datatypes are summarized for individual genomes and across taxonomic levels. All genomes in PATRIC, currently more than 10,000, are consistently annotated using RAST, the Rapid Annotations using Subsystems Technology. Summaries of different data types are also provided for individual genes, where comparisons of different annotations are available, and also include available transcriptomic data. PATRIC provides a variety of ways for researchers to find data of interest and a private workspace where they can store both genomic and gene associations, and their own private data. Both private and public data can be analyzed together using a suite of tools to perform comparative genomic or transcriptomic analysis. PATRIC also includes integrated information related to disease and PPIs. All the data and integrated analysis and visualization tools are freely available. This manuscript describes updates to the PATRIC since its initial report in the 2007 NAR Database Issue.</description><subject>Bacteria - classification</subject><subject>Bacteria - genetics</subject><subject>Bacterial Infections - microbiology</subject><subject>Bacterial Proteins - chemistry</subject><subject>Bacterial Proteins - metabolism</subject><subject>Bacterial Typing Techniques</subject><subject>Databases, Genetic</subject><subject>Gene Expression Profiling</subject><subject>Genome, Bacterial</subject><subject>Genomics</subject><subject>Humans</subject><subject>Internet</subject><subject>IV. Viruses, bacteria, protozoa and fungi</subject><subject>Protein Conformation</subject><subject>Protein Interaction Mapping</subject><issn>0305-1048</issn><issn>1362-4962</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkM1Lw0AQxRdRbK2evEuOgsbuVz72IpTgR6GgSD0vk82kXU2TupsI_e9NaS16GObBe7wZfoRcMnrHqBLjGtx48dn2Wh2RIRMxD6WK-TEZUkGjkFGZDsiZ9x-UMskieUoGXHIeCS6GJHudzN-m2W3QLjHIwbToLFRBbhtbl41bQWuNDwpoIQePAdRFP1BtvPWBQ990zuA5OSmh8nix3yPy_vgwz57D2cvTNJvMQiNT1Ya5KAAhEbFMpRJAwTCZpwWNEyziUmDBMTe83LpK8ZgniHFEJapeRGmpxIjc73rXXb7CwmDdOqj02tkVuI1uwOr_Tm2XetF8a6H6IhX1Bdf7Atd8dehbvbLeYFVBjU3nNZOKJhFXlPbRm13UuMZ7h-XhDKN6i1332PUee5---vvZIfvLWfwA07N_9Q</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Wattam, Alice R</creator><creator>Abraham, David</creator><creator>Dalay, Oral</creator><creator>Disz, Terry L</creator><creator>Driscoll, Timothy</creator><creator>Gabbard, Joseph L</creator><creator>Gillespie, Joseph J</creator><creator>Gough, Roger</creator><creator>Hix, Deborah</creator><creator>Kenyon, Ronald</creator><creator>Machi, Dustin</creator><creator>Mao, Chunhong</creator><creator>Nordberg, Eric K</creator><creator>Olson, Robert</creator><creator>Overbeek, Ross</creator><creator>Pusch, Gordon D</creator><creator>Shukla, Maulik</creator><creator>Schulman, Julie</creator><creator>Stevens, Rick L</creator><creator>Sullivan, Daniel E</creator><creator>Vonstein, Veronika</creator><creator>Warren, Andrew</creator><creator>Will, Rebecca</creator><creator>Wilson, Meredith J C</creator><creator>Yoo, Hyun Seung</creator><creator>Zhang, Chengdong</creator><creator>Zhang, Yan</creator><creator>Sobral, Bruno W</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140101</creationdate><title>PATRIC, the bacterial bioinformatics database and analysis resource</title><author>Wattam, Alice R ; Abraham, David ; Dalay, Oral ; Disz, Terry L ; Driscoll, Timothy ; Gabbard, Joseph L ; Gillespie, Joseph J ; Gough, Roger ; Hix, Deborah ; Kenyon, Ronald ; Machi, Dustin ; Mao, Chunhong ; Nordberg, Eric K ; Olson, Robert ; Overbeek, Ross ; Pusch, Gordon D ; Shukla, Maulik ; Schulman, Julie ; Stevens, Rick L ; Sullivan, Daniel E ; Vonstein, Veronika ; Warren, Andrew ; Will, Rebecca ; Wilson, Meredith J C ; Yoo, Hyun Seung ; Zhang, Chengdong ; Zhang, Yan ; Sobral, Bruno W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c489t-b3daea73648493a0ac14b8d067ed6f3ed2ebc2f4849992627ee6504e97ee58f93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Bacteria - classification</topic><topic>Bacteria - genetics</topic><topic>Bacterial Infections - microbiology</topic><topic>Bacterial Proteins - chemistry</topic><topic>Bacterial Proteins - metabolism</topic><topic>Bacterial Typing Techniques</topic><topic>Databases, Genetic</topic><topic>Gene Expression Profiling</topic><topic>Genome, Bacterial</topic><topic>Genomics</topic><topic>Humans</topic><topic>Internet</topic><topic>IV. Viruses, bacteria, protozoa and fungi</topic><topic>Protein Conformation</topic><topic>Protein Interaction Mapping</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wattam, Alice R</creatorcontrib><creatorcontrib>Abraham, David</creatorcontrib><creatorcontrib>Dalay, Oral</creatorcontrib><creatorcontrib>Disz, Terry L</creatorcontrib><creatorcontrib>Driscoll, Timothy</creatorcontrib><creatorcontrib>Gabbard, Joseph L</creatorcontrib><creatorcontrib>Gillespie, Joseph J</creatorcontrib><creatorcontrib>Gough, Roger</creatorcontrib><creatorcontrib>Hix, Deborah</creatorcontrib><creatorcontrib>Kenyon, Ronald</creatorcontrib><creatorcontrib>Machi, Dustin</creatorcontrib><creatorcontrib>Mao, Chunhong</creatorcontrib><creatorcontrib>Nordberg, Eric K</creatorcontrib><creatorcontrib>Olson, Robert</creatorcontrib><creatorcontrib>Overbeek, Ross</creatorcontrib><creatorcontrib>Pusch, Gordon D</creatorcontrib><creatorcontrib>Shukla, Maulik</creatorcontrib><creatorcontrib>Schulman, Julie</creatorcontrib><creatorcontrib>Stevens, Rick L</creatorcontrib><creatorcontrib>Sullivan, Daniel E</creatorcontrib><creatorcontrib>Vonstein, Veronika</creatorcontrib><creatorcontrib>Warren, Andrew</creatorcontrib><creatorcontrib>Will, Rebecca</creatorcontrib><creatorcontrib>Wilson, Meredith J C</creatorcontrib><creatorcontrib>Yoo, Hyun Seung</creatorcontrib><creatorcontrib>Zhang, Chengdong</creatorcontrib><creatorcontrib>Zhang, Yan</creatorcontrib><creatorcontrib>Sobral, Bruno W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nucleic acids research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wattam, Alice R</au><au>Abraham, David</au><au>Dalay, Oral</au><au>Disz, Terry L</au><au>Driscoll, Timothy</au><au>Gabbard, Joseph L</au><au>Gillespie, Joseph J</au><au>Gough, Roger</au><au>Hix, Deborah</au><au>Kenyon, Ronald</au><au>Machi, Dustin</au><au>Mao, Chunhong</au><au>Nordberg, Eric K</au><au>Olson, Robert</au><au>Overbeek, Ross</au><au>Pusch, Gordon D</au><au>Shukla, Maulik</au><au>Schulman, Julie</au><au>Stevens, Rick L</au><au>Sullivan, Daniel E</au><au>Vonstein, Veronika</au><au>Warren, Andrew</au><au>Will, Rebecca</au><au>Wilson, Meredith J C</au><au>Yoo, Hyun Seung</au><au>Zhang, Chengdong</au><au>Zhang, Yan</au><au>Sobral, Bruno W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PATRIC, the bacterial bioinformatics database and analysis resource</atitle><jtitle>Nucleic acids research</jtitle><addtitle>Nucleic Acids Res</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>42</volume><issue>Database issue</issue><spage>D581</spage><epage>D591</epage><pages>D581-D591</pages><issn>0305-1048</issn><eissn>1362-4962</eissn><abstract>The Pathosystems Resource Integration Center (PATRIC) is the all-bacterial Bioinformatics Resource Center (BRC) (http://www.patricbrc.org). A joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded BRCs, PATRIC provides researchers with an online resource that stores and integrates a variety of data types [e.g. genomics, transcriptomics, protein-protein interactions (PPIs), three-dimensional protein structures and sequence typing data] and associated metadata. Datatypes are summarized for individual genomes and across taxonomic levels. All genomes in PATRIC, currently more than 10,000, are consistently annotated using RAST, the Rapid Annotations using Subsystems Technology. Summaries of different data types are also provided for individual genes, where comparisons of different annotations are available, and also include available transcriptomic data. PATRIC provides a variety of ways for researchers to find data of interest and a private workspace where they can store both genomic and gene associations, and their own private data. Both private and public data can be analyzed together using a suite of tools to perform comparative genomic or transcriptomic analysis. PATRIC also includes integrated information related to disease and PPIs. All the data and integrated analysis and visualization tools are freely available. This manuscript describes updates to the PATRIC since its initial report in the 2007 NAR Database Issue.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>24225323</pmid><doi>10.1093/nar/gkt1099</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0305-1048 |
| ispartof | Nucleic acids research, 2014-01, Vol.42 (Database issue), p.D581-D591 |
| issn | 0305-1048 1362-4962 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3965095 |
| source | Oxford Journals Open Access Collection; MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Bacteria - classification Bacteria - genetics Bacterial Infections - microbiology Bacterial Proteins - chemistry Bacterial Proteins - metabolism Bacterial Typing Techniques Databases, Genetic Gene Expression Profiling Genome, Bacterial Genomics Humans Internet IV. Viruses, bacteria, protozoa and fungi Protein Conformation Protein Interaction Mapping |
| title | PATRIC, the bacterial bioinformatics database and analysis resource |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T15%3A49%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=PATRIC,%20the%20bacterial%20bioinformatics%20database%20and%20analysis%20resource&rft.jtitle=Nucleic%20acids%20research&rft.au=Wattam,%20Alice%20R&rft.date=2014-01-01&rft.volume=42&rft.issue=Database%20issue&rft.spage=D581&rft.epage=D591&rft.pages=D581-D591&rft.issn=0305-1048&rft.eissn=1362-4962&rft_id=info:doi/10.1093/nar/gkt1099&rft_dat=%3Cproquest_pubme%3E1490752900%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1490752900&rft_id=info:pmid/24225323&rfr_iscdi=true |