DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells

Timely removal of oxidatively damaged proteins is crit- ical for cells exposed to oxidative stresses; however, cellular mechanism for clearing oxidized proteins is not clear. Our study reveals a novel type of protein modifi- cation that may play a role in targeting oxidized proteins and remove them....

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Veröffentlicht in:Protein & cell 2014-02, Vol.5 (2), p.124-140
Hauptverfasser: Zhang, Yinghao, Chang, Fang-Mei, Huang, Jianjun, Junco, Jacob J., Maffi, Shivani K., Pridgen, Hannah I., Catano, Gabriel, Dang, Hong, Ding, Xiang, Yang, Fuquan, Kim, Dae Joon, Slaga, Thomas J., He, Rongqiao, Wei, Sung-Jen
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Sprache:eng
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