Evolution and genetic diversity of the Spain23F-ST81 clone causing adult invasive pneumococcal disease in Barcelona (1990–2012)

Objectives We aimed to analyse the clinical epidemiology and genetic diversity of invasive pneumococcal disease (IPD) episodes attributed to the Spain23F-ST81 (PMEN1) clone. Methods Fifty-eight (2.7%) of 2117 invasive pneumococci isolated from adult patients during the 1990–2012 period shared a PFGE...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2014-04, Vol.69 (4), p.924-931
Hauptverfasser:	Domenech, A., Ardanuy, C., Grau, I., Calatayud, L., Pallares, R., Fenoll, A., Brueggemann, A. B., Liñares, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over DNA, Bacterial - genetics Electrophoresis, Gel, Pulsed-Field Evolution, Molecular Female Genes, Bacterial Genetic Variation Genotype Humans Male Middle Aged Molecular Epidemiology Multilocus Sequence Typing Original Research Pneumococcal Infections - epidemiology Pneumococcal Infections - microbiology Polymerase Chain Reaction Spain - epidemiology Streptococcus pneumoniae - classification Streptococcus pneumoniae - genetics Streptococcus pneumoniae - isolation & purification Young Adult
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