Encore: Genetic Association Interaction Network Centrality Pipeline and Application to SLE Exome Data

ABSTRACT Open source tools are needed to facilitate the construction, analysis, and visualization of gene‐gene interaction networks for sequencing data. To address this need, we present Encore, an open source network analysis pipeline for genome‐wide association studies and rare variant data. Encore...

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Veröffentlicht in:	Genetic epidemiology 2013-09, Vol.37 (6), p.614-621
Hauptverfasser:	Davis, Nicholas A., Lareau, Caleb A., White, Bill C., Pandey, Ahwan, Wiley, Graham, Montgomery, Courtney G., Gaffney, Patrick M., McKinney, B. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms epistasis network Epistasis, Genetic Exome Gene Regulatory Networks Generalized linear models Genes Genetic Predisposition to Disease Genome-Wide Association Study HLA-DR beta-Chains - genetics Humans Linkage Disequilibrium Lupus Erythematosus, Systemic - genetics machine learning Medical research NADPH Oxidases - genetics network analysis network centrality Sialyltransferases - genetics Software Systemic Lupus Erythematous
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