Synergistic Combination of Hyperoxygenation and Radiotherapy by Repeated Assessments of Tumor pO2 with EPR Oximetry

The effect of hyperoxygenation with carbogen (95% O2 + 5% CO2) inhalation on RIF-1 tumor pO2and its consequence on growth inhibition with fractionated radiotherapy is reported. The temporal changes in the tumor pO2 were assessed by in vivo Electron Paramagnetic Resonance (EPR) oximetry in mice breat...

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Veröffentlicht in:	Journal of radiation research 2011, Vol.52 (5), p.568-574
Hauptverfasser:	Hou, Huagang, Dong, Ruhong, Lariviere, Jean P., Mupparaju, Sriram P., Swartz, Harold M., Khan, Nadeem
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carbon Dioxide - administration & dosage Cell Line, Tumor Combined Modality Therapy Electron Spin Resonance Spectroscopy Female Hypoxia - metabolism Hypoxia - radiotherapy Hypoxia - therapy Mice Mice, Inbred C3H Neoplasms, Radiation-Induced - metabolism Neoplasms, Radiation-Induced - radiotherapy Neoplasms, Radiation-Induced - therapy Oximetry Oxygen - administration & dosage Oxygen - metabolism Radiation Tolerance Radiation-Sensitizing Agents - administration & dosage Sarcoma, Experimental - metabolism Sarcoma, Experimental - radiotherapy Sarcoma, Experimental - therapy
Online-Zugang:	Volltext
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