Neuroimaging and Other Biomarkers for Alzheimer's Disease: The Changing Landscape of Early Detection

The goal of this review is to provide an overview of biomarkers for Alzheimer's disease (AD), with emphasis on neuroimaging and cerebrospinal fluid (CSF) biomarkers. We first review biomarker changes in patients with late-onset AD, including findings from studies using structural and functional...

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Veröffentlicht in:	Annual review of clinical psychology 2013-01, Vol.9 (1), p.621-648
Hauptverfasser:	Risacher, Shannon L, Saykin, Andrew J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - cerebrospinal fluid Alzheimer Disease - diagnosis Alzheimer Disease - pathology Biomarkers - cerebrospinal fluid cerebrospinal fluid (CSF) Cognitive Dysfunction - cerebrospinal fluid Cognitive Dysfunction - diagnosis Cognitive Dysfunction - pathology Early Diagnosis functional MRI (fMRI) genetics Humans magnetic resonance imaging (MRI) Magnetic Resonance Imaging - methods mild cognitive impairment (MCI) Neuroimaging - methods positron emission tomography (PET) Positron-Emission Tomography - methods preclinical Alzheimer's disease (AD) Prodromal Symptoms
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