Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins

hnRNP A1 is a pre‐mRNA binding protein that antagonizes the alternative splicing activity of splicing factors SF2/ASF or SC35, causing activation of distal 5′ splice sites. The structural requirements for hnRNP A1 function were determined by mutagenesis of recombinant human hnRNP A1. Two conserved P...

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Veröffentlicht in:	The EMBO journal 1994-11, Vol.13 (22), p.5483-5495
Hauptverfasser:	Mayeda, A., Munroe, S.H., Cáceres, J.F., Krainer, A.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Heterogeneous Nuclear Ribonucleoprotein A1 Heterogeneous-Nuclear Ribonucleoprotein Group A-B Heterogeneous-Nuclear Ribonucleoproteins Humans Molecular Sequence Data Nucleic Acid Conformation Nucleic Acid Denaturation Polymerase Chain Reaction Recombinant Fusion Proteins - metabolism Ribonucleoproteins - chemistry Ribonucleoproteins - classification Ribonucleoproteins - genetics Ribonucleoproteins - physiology RNA Precursors - metabolism RNA Splicing
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