Lessons learned from gene expression profiling of cutaneous T-cell lymphoma

Summary Gene expression studies of cutaneous T‐cell lymphoma (CTCL) span a decade, yet the pathogenesis is poorly understood and diagnosis remains a challenge. This review examines the varied approaches to gene expression analysis of CTCL, with emphasis on cell populations, control selection and exp...

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Veröffentlicht in:	British journal of dermatology (1951) 2013-12, Vol.169 (6), p.1188-1197
Hauptverfasser:	Dulmage, B.O., Geskin, L.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Death - genetics Cell Differentiation - genetics Cell Differentiation - immunology Dermatology Gene Expression Profiling Genes, Neoplasm - genetics Genetic Heterogeneity Hematologic and hematopoietic diseases Humans Immunity, Cellular - genetics Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, T-Cell, Cutaneous - genetics Lymphoma, T-Cell, Cutaneous - immunology Medical sciences Neoplasm Proteins - genetics Receptors, Transforming Growth Factor beta - metabolism Receptors, Tumor Necrosis Factor - metabolism RNA, Untranslated - genetics Skin Neoplasms - genetics Skin Neoplasms - immunology Th2 Cells - immunology
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