Pathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapy

Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) are significant causes of morbidity and mortality in children and young adults. ADPKD, with an incidence of 1:400 to 1:1,000, affects more than 13 million individuals worldwide and is a maj...

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Veröffentlicht in:	Pediatric research 2014-01, Vol.75 (1-2), p.148-157
Hauptverfasser:	Sweeney, William E., Avner, Ellis D.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/420/2489/144 692/699/1585/1589 692/700/1720 Adolescent Age Factors Animals Child Child, Preschool Genetic Predisposition to Disease Humans Incidence Infant Kidney - metabolism Kidney - physiopathology Medicine & Public Health Pediatric Surgery Pediatrics Phenotype Polycystic Kidney, Autosomal Dominant - epidemiology Polycystic Kidney, Autosomal Dominant - genetics Polycystic Kidney, Autosomal Dominant - metabolism Polycystic Kidney, Autosomal Dominant - physiopathology Polycystic Kidney, Autosomal Dominant - therapy Polycystic Kidney, Autosomal Recessive - epidemiology Polycystic Kidney, Autosomal Recessive - genetics Polycystic Kidney, Autosomal Recessive - metabolism Polycystic Kidney, Autosomal Recessive - physiopathology Polycystic Kidney, Autosomal Recessive - therapy Prognosis review Risk Factors Signal Transduction
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