Specific Contactin N-Glycans Are Implicated in Neurofascin Binding and Autoimmune Targeting in Peripheral Neuropathies

Cell adhesion molecules (CAMs) play a crucial role in the formation of the nodes of Ranvier and in the rapid propagation of the nerve impulses along myelinated axons. These CAMs are the targets of autoimmunity in inflammatory neuropathies. We recently showed that a subgroup of patients with aggressi...

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Veröffentlicht in:The Journal of biological chemistry 2014-03, Vol.289 (11), p.7907-7918
Hauptverfasser: Labasque, Marilyne, Hivert, Bruno, Nogales-Gadea, Gisela, Querol, Luis, Illa, Isabel, Faivre-Sarrailh, Catherine
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Sprache:eng
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