Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor

Mesenchymal stem cells (MSCs) are typically defined by their in vitro characteristics, and as a consequence the in vivo identity of MSCs and their niches are poorly understood. To address this issue, we used lineage tracing in a mouse incisor model and identified the neurovascular bundle (NVB) as an...

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Veröffentlicht in:	Cell stem cell 2014-02, Vol.14 (2), p.160-173
Hauptverfasser:	Zhao, Hu, Feng, Jifan, Seidel, Kerstin, Shi, Songtao, Klein, Ophir, Sharpe, Paul, Chai, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Antigens - metabolism Arteries - cytology Arteries - metabolism Biomarkers - metabolism Guinea Pigs Hedgehog Proteins - metabolism Homeostasis Incisor - blood supply Incisor - cytology Incisor - innervation Kruppel-Like Transcription Factors - metabolism Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism Mesoderm - pathology Mice Models, Biological Pericytes - cytology Pericytes - metabolism Proteoglycans - metabolism Sensory Receptor Cells - cytology Sensory Receptor Cells - metabolism Staining and Labeling Stem Cell Niche Zinc Finger Protein GLI1
Online-Zugang:	Volltext
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