C1q binding to Dengue Virus inhibits infection of THP-1 and cellular inflammatory responses

Dengue virus infection elicits a spectrum of clinical presentations ranging from asymptomatic to severe disease. The mechanisms leading to severe dengue are not known, however it has been reported that the complement system is hyper-activated in severe dengue. Screening of complement proteins demons...

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Veröffentlicht in:Virus research 2013-11, Vol.179, p.231-234
Hauptverfasser: Douradinha, Bruno, McBurney, Sean P., de Melo, Klecia M. Soares, Smith, Amanda P., Krishna, Neel K., Barratt-Boyes, Simon M., Evans, Jared D., Nascimento, Eduardo J. M., Marques, Ernesto T. A
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Sprache:eng
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