Enhanced tumor delivery and antitumor activity in vivo of liposomal doxorubicin modified with MCF-7-specific phage fusion protein

Abstract A novel strategy to improve the therapeutic index of chemotherapy has been developed by the integration of nanotechnology with phage technique. The objective of this study was to combine phage display, identifying tumor-targeting ligands, with a liposomal nanocarrier for targeted delivery o...

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Veröffentlicht in:Nanomedicine 2014-02, Vol.10 (2), p.421-430
Hauptverfasser: Wang, Tao, PhD, Hartner, William C., PhD, Gillespie, James W., BS, Praveen, Kulkarni P., PhD, Yang, Shenghong, PhD, Mei, Leslie A., BS, Petrenko, Valery A., PhD, Torchilin, Vladimir P., PhD
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Sprache:eng
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