Picoelectrospray Ionization Mass Spectrometry Using Narrow-Bore Chemically Etched Emitters

Electrospray ionization mass spectrometry (ESI-MS) at flow rates below ~10 nL/min has been only sporadically explored because of difficulty in reproducibly fabricating emitters that can operate at lower flow rates. Here we demonstrate narrow orifice chemically etched emitters for stable electrospray...

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Veröffentlicht in:	Journal of the American Society for Mass Spectrometry 2014-01, Vol.25 (1), p.30-36
Hauptverfasser:	Marginean, Ioan, Tang, Keqi, Smith, Richard D., Kelly, Ryan T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Bioinformatics Biological properties Biotechnology Chemistry Chemistry and Materials Science Dilution Efficiency Electrospraying Emitters Environmental Molecular Sciences Laboratory Flow velocity Ionization Ions Low concentrations Mass spectrometry Organic Chemistry Peptides Peptides - chemistry Proteomics Research Article Scientific imaging Signal-To-Noise Ratio Spectrometry, Mass, Electrospray Ionization - methods Spectroscopy
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