Mechanisms underlying the development of the electrocardiographic and arrhythmic manifestations of early repolarization syndrome

Abstract Early repolarization pattern in the ECG has been associated with increased risk for ventricular tachycardia/fibrillation (VT/VF), particularly when manifest in inferior leads. This study examines the mechanisms underlying VT/VF in early repolarization syndrome (ERS). Transmembrane action po...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 2014-03, Vol.68, p.20-28
Hauptverfasser:	Koncz, István, Gurabi, Zsolt, Patocskai, Bence, Panama, Brian K, Szél, Tamás, Hu, Dan, Barajas-Martínez, Hector, Antzelevitch, Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Animals Anti-Arrhythmia Agents - pharmacology Arrhythmias, Cardiac - etiology Arrhythmias, Cardiac - physiopathology Brugada Syndrome Cardiac Conduction System Disease Cardiovascular Dogs Electrophysiology Female Heart Conduction System - abnormalities Heart Conduction System - drug effects Heart Conduction System - physiopathology Heart Ventricles - physiopathology In Vitro Techniques J wave syndrome Male Myocardial Contraction Parasympathetic tone Patch-Clamp Techniques Pericardium - physiopathology Phenylurea Compounds - pharmacology Syndrome Tetrazoles - pharmacology Transient outward potassium current Ventricular fibrillation Verapamil - pharmacology
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